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The Arginine Decarboxylase Pathways of Host and Pathogen Interact to Impact Inflammatory Pathways in the Lung

The arginine decarboxylase pathway, which converts arginine to agmatine, is present in both humans and most bacterial pathogens. In humans agmatine is a neurotransmitter with affinities towards α2-adrenoreceptors, serotonin receptors, and may inhibit nitric oxide synthase. In bacteria agmatine serve...

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Detalles Bibliográficos
Autores principales: Paulson, Nick B., Gilbertsen, Adam J., Dalluge, Joseph J., Welchlin, Cole W., Hughes, John, Han, Wei, Blackwell, Timothy S., Laguna, Theresa A., Williams, Bryan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211729/
https://www.ncbi.nlm.nih.gov/pubmed/25350753
http://dx.doi.org/10.1371/journal.pone.0111441