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The Arginine Decarboxylase Pathways of Host and Pathogen Interact to Impact Inflammatory Pathways in the Lung
The arginine decarboxylase pathway, which converts arginine to agmatine, is present in both humans and most bacterial pathogens. In humans agmatine is a neurotransmitter with affinities towards α2-adrenoreceptors, serotonin receptors, and may inhibit nitric oxide synthase. In bacteria agmatine serve...
Autores principales: | Paulson, Nick B., Gilbertsen, Adam J., Dalluge, Joseph J., Welchlin, Cole W., Hughes, John, Han, Wei, Blackwell, Timothy S., Laguna, Theresa A., Williams, Bryan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211729/ https://www.ncbi.nlm.nih.gov/pubmed/25350753 http://dx.doi.org/10.1371/journal.pone.0111441 |
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