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Clinical utility of recombinant adenoviral human p53 gene therapy: current perspectives

Gene therapy has promised to be a highly effective antitumor treatment by introducing a tumor suppressor gene or the abrogation of an oncogene. Among the potential therapeutic transgenes, the tumor suppressor gene p53 serves as an attractive target. Restoration of wild-type p53 function in tumors ca...

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Detalles Bibliográficos
Autores principales: Chen, Guang-xia, Zhang, Shu, He, Xiao-hua, Liu, Shi-yu, Ma, Chao, Zou, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211860/
https://www.ncbi.nlm.nih.gov/pubmed/25364261
http://dx.doi.org/10.2147/OTT.S50483