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Co-association of methotrexate and SPIONs into anti-CD64 antibody-conjugated PLGA nanoparticles for theranostic application

BACKGROUND: Rheumatoid arthritis (RA) is an autoimmune disease with severe consequences for the quality of life of sufferers. Regrettably, the inflammatory process involved remains unclear, and finding successful therapies as well as new means for its early diagnosis have proved to be daunting tasks...

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Detalles Bibliográficos
Autores principales: Moura, Catarina Costa, Segundo, Marcela A, Neves, José das, Reis, Salette, Sarmento, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211909/
https://www.ncbi.nlm.nih.gov/pubmed/25364249
http://dx.doi.org/10.2147/IJN.S68440