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Co-association of methotrexate and SPIONs into anti-CD64 antibody-conjugated PLGA nanoparticles for theranostic application
BACKGROUND: Rheumatoid arthritis (RA) is an autoimmune disease with severe consequences for the quality of life of sufferers. Regrettably, the inflammatory process involved remains unclear, and finding successful therapies as well as new means for its early diagnosis have proved to be daunting tasks...
Autores principales: | Moura, Catarina Costa, Segundo, Marcela A, Neves, José das, Reis, Salette, Sarmento, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211909/ https://www.ncbi.nlm.nih.gov/pubmed/25364249 http://dx.doi.org/10.2147/IJN.S68440 |
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