The sustained-release behavior and in vitro and in vivo transfection of pEGFP-loaded core-shell-structured chitosan-based composite particles

Novel submicron core-shell-structured chitosan-based composite particles encapsulated with enhanced green fluorescent protein plasmids (pEGFP) were prepared by complex coacervation method. The core was pEGFP-loaded thiolated N-alkylated chitosan (TACS) and the shell was pH- and temperature-responsiv...

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Detalles Bibliográficos
Autores principales: Wang, Yun, Lin, Fu-xing, Zhao, Yu, Wang, Mo-zhen, Ge, Xue-wu, Gong, Zheng-xing, Bao, Dan-dan, Gu, Yu-fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211910/
https://www.ncbi.nlm.nih.gov/pubmed/25364253
http://dx.doi.org/10.2147/IJN.S58104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211910/
https://www.ncbi.nlm.nih.gov/pubmed/25364253
http://dx.doi.org/10.2147/IJN.S58104

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