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Nucleostemin stabilizes ARF by inhibiting the ubiquitin ligase ULF
Up-regulated expression of nucleolar GTPase Nucleostemin (NS) has been associated with increased cellular proliferation potential and tumor malignancy during cancer development. Recent reports attribute the growth regulatory effects of NS protein to its role in facilitating ribosome production. Howe...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212020/ https://www.ncbi.nlm.nih.gov/pubmed/24769896 http://dx.doi.org/10.1038/onc.2014.103 |