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Nucleostemin stabilizes ARF by inhibiting the ubiquitin ligase ULF

Up-regulated expression of nucleolar GTPase Nucleostemin (NS) has been associated with increased cellular proliferation potential and tumor malignancy during cancer development. Recent reports attribute the growth regulatory effects of NS protein to its role in facilitating ribosome production. Howe...

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Detalles Bibliográficos
Autores principales: Lo, Dorothy, Zhang, Yiwei, Dai, Mu-Shui, Sun, Xiao-Xin, Zeng, Shelya X., Lu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212020/
https://www.ncbi.nlm.nih.gov/pubmed/24769896
http://dx.doi.org/10.1038/onc.2014.103