5-aminoimidazole-4-carboxamide Riboside Induces Apoptosis Through AMP-activated Protein Kinase-independent and NADPH Oxidase-dependent Pathways

It is debatable whether AMP-activated protein kinase (AMPK) activation is involved in anti-apoptotic or pro-apoptotic signaling. AICAR treatment increases AMPK-α1 phosphorylation, decreases intracellular reactive oxygen species (ROS) levels, and significantly increases Annexin V-positive cells, DNA...

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Detalles Bibliográficos
Autores principales: Wi, Sae Mi, Lee, Ki-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212085/
https://www.ncbi.nlm.nih.gov/pubmed/25360075
http://dx.doi.org/10.4110/in.2014.14.5.241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212085/
https://www.ncbi.nlm.nih.gov/pubmed/25360075
http://dx.doi.org/10.4110/in.2014.14.5.241

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