Cargando…

RRHP: a tag-based approach for 5-hydroxymethylcytosine mapping at single-site resolution

Current methods for genomic mapping of 5-hydroxymethylcytosine (5hmC) have been limited by either costly sequencing depth, high DNA input, or lack of single-base resolution. We present an approach called Reduced Representation 5-Hydroxymethylcytosine Profiling (RRHP) to map 5hmC sites at single-base...

Descripción completa

Detalles Bibliográficos
Autores principales: Petterson, Adam, Chung, Tzu Hung, Tan, Darany, Sun, Xueguang, Jia, Xi-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212096/
https://www.ncbi.nlm.nih.gov/pubmed/25248841
http://dx.doi.org/10.1186/s13059-014-0456-5