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RRHP: a tag-based approach for 5-hydroxymethylcytosine mapping at single-site resolution
Current methods for genomic mapping of 5-hydroxymethylcytosine (5hmC) have been limited by either costly sequencing depth, high DNA input, or lack of single-base resolution. We present an approach called Reduced Representation 5-Hydroxymethylcytosine Profiling (RRHP) to map 5hmC sites at single-base...
Autores principales: | Petterson, Adam, Chung, Tzu Hung, Tan, Darany, Sun, Xueguang, Jia, Xi-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212096/ https://www.ncbi.nlm.nih.gov/pubmed/25248841 http://dx.doi.org/10.1186/s13059-014-0456-5 |
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