Claudin-4 controls the receptor tyrosine kinase EphA2 pro-oncogenic switch through β-catenin

BACKGROUND: The EphA2 receptor, which is expressed in many types of cancer, is activated by two different mechanisms. Activation by engagement with one of its ephrin ligands is anti-oncogenic whereas phosphorylation of S897 by AKT increases migration, invasion and metastasis. Down-regulation of clau...

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Detalles Bibliográficos
Autores principales: Shang, Xiying, Lin, Xinjian, Howell, Stephen B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212103/
https://www.ncbi.nlm.nih.gov/pubmed/25344320
http://dx.doi.org/10.1186/s12964-014-0059-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212103/
https://www.ncbi.nlm.nih.gov/pubmed/25344320
http://dx.doi.org/10.1186/s12964-014-0059-5

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