p38 MAP kinase-mediated NMDA receptor-dependent suppression of hippocampal hypersynchronicity in a mouse model of Alzheimer’s disease

Hypersynchronicity of neuronal brain circuits is a feature of Alzheimer’s disease (AD). Mouse models of AD expressing mutated forms of the amyloid-β precursor protein (APP), a central protein involved in AD pathology, show cortical hypersynchronicity. We studied hippocampal circuitry in APP23 transg...

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Detalles Bibliográficos
Autores principales: Ittner, Arne A, Gladbach, Amadeus, Bertz, Josefine, Suh, Lisa S, Ittner, Lars M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212118/
https://www.ncbi.nlm.nih.gov/pubmed/25331068
http://dx.doi.org/10.1186/s40478-014-0149-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212118/
https://www.ncbi.nlm.nih.gov/pubmed/25331068
http://dx.doi.org/10.1186/s40478-014-0149-z

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