A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis

BACKGROUND: New drugs effective against adult filariae (macrofilaricides) would accelerate the elimination of lymphatic filariasis and onchocerciasis. Anti-Onchocerca drug development is hampered by the lack of a facile model. We postulated that SCID mice could be developed as a fmacrofilaricide scr...

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Detalles Bibliográficos
Autores principales: Halliday, Alice, Guimaraes, Ana F, Tyrer, Hayley E, Metuge, Haelly Mejane, Patrick, Chounna Ndongmo Winston, Arnaud, Kengne-Ouafo Jonas, Kwenti, Tayong Dizzle Bita, Forsbrook, George, Steven, Andrew, Cook, Darren, Enyong, Peter, Wanji, Samuel, Taylor, Mark J, Turner, Joseph D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212127/
https://www.ncbi.nlm.nih.gov/pubmed/25338621
http://dx.doi.org/10.1186/s13071-014-0472-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212127/
https://www.ncbi.nlm.nih.gov/pubmed/25338621
http://dx.doi.org/10.1186/s13071-014-0472-z

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