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Reversal of Anchorage-Independent Multicellular Spheroid into a Monolayer Mimics a Metastatic Model
Lack of an in vitro model of metastasis has been a major impediment in understanding the molecular regulation of metastatic processes, and identification of specific therapeutic targets. We have established an in vitro model which displayed the signatures of metastatic phenotype such as migration, i...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212233/ https://www.ncbi.nlm.nih.gov/pubmed/25351825 http://dx.doi.org/10.1038/srep06816 |