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Reversal of Anchorage-Independent Multicellular Spheroid into a Monolayer Mimics a Metastatic Model

Lack of an in vitro model of metastasis has been a major impediment in understanding the molecular regulation of metastatic processes, and identification of specific therapeutic targets. We have established an in vitro model which displayed the signatures of metastatic phenotype such as migration, i...

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Detalles Bibliográficos
Autores principales: Kunjithapatham, Rani, Karthikeyan, Swathi, Geschwind, Jean-Francois, Kieserman, Esther, Lin, MingDe, Fu, De-Xue, Ganapathy-Kanniappan, Shanmugasundaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212233/
https://www.ncbi.nlm.nih.gov/pubmed/25351825
http://dx.doi.org/10.1038/srep06816