A Preclinical Study Combining the DNA Repair Inhibitor Dbait with Radiotherapy for the Treatment of Melanoma()

Melanomas are highly radioresistant tumors, mainly due to efficient DNA double-strand break (DSB) repair. Dbait (which stands for DNA strand break bait) molecules mimic DSBs and trap DNA repair proteins, thereby inhibiting repair of DNA damage induced by radiation therapy (RT). First, the cytotoxic...

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Detalles Bibliográficos
Autores principales: Biau, Julian, Devun, Flavien, Jdey, Wael, Kotula, Ewa, Quanz, Maria, Chautard, Emmanuel, Sayarath, Mano, Sun, Jian-Sheng, Verrelle, Pierre, Dutreix, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212251/
https://www.ncbi.nlm.nih.gov/pubmed/25379020
http://dx.doi.org/10.1016/j.neo.2014.08.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212251/
https://www.ncbi.nlm.nih.gov/pubmed/25379020
http://dx.doi.org/10.1016/j.neo.2014.08.008

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