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Methods for integration of transcriptomic data in genome-scale metabolic models

Several computational methods have been developed that integrate transcriptomic data with genome-scale metabolic reconstructions to infer condition-specific system-wide intracellular metabolic flux distributions. In this mini-review, we describe each of these methods published to date with categoriz...

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Detalles Bibliográficos
Autores principales: Kim, Min Kyung, Lun, Desmond S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212280/
https://www.ncbi.nlm.nih.gov/pubmed/25379144
http://dx.doi.org/10.1016/j.csbj.2014.08.009