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Evolution of Metallo-β-lactamases: Trends Revealed by Natural Diversity and in vitro Evolution
The production of β-lactamase enzymes is one of the most distributed resistance mechanisms towards β-lactam antibiotics. Metallo-β-lactamases constitute a worrisome group of these kinds of enzymes, since they present a broad spectrum profile, being able to hydrolyze not only penicillins, but also th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212336/ https://www.ncbi.nlm.nih.gov/pubmed/25364574 http://dx.doi.org/10.3390/antibiotics3030285 |