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Evolution of Metallo-β-lactamases: Trends Revealed by Natural Diversity and in vitro Evolution
The production of β-lactamase enzymes is one of the most distributed resistance mechanisms towards β-lactam antibiotics. Metallo-β-lactamases constitute a worrisome group of these kinds of enzymes, since they present a broad spectrum profile, being able to hydrolyze not only penicillins, but also th...
Autores principales: | Meini, María-Rocío, Llarrull, Leticia I., Vila, Alejandro J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212336/ https://www.ncbi.nlm.nih.gov/pubmed/25364574 http://dx.doi.org/10.3390/antibiotics3030285 |
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