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LRP4 antibodies in serum and CSF from amyotrophic lateral sclerosis patients

OBJECTIVE: Amyotrophic lateral sclerosis (ALS) and myasthenia gravis (MG) are caused, respectively, by motor neuron degeneration and neuromuscular junction (NMJ) dysfunction. The membrane protein LRP4 is crucial in the development and function of motor neurons and NMJs and LRP4 autoantibodies have b...

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Detalles Bibliográficos
Autores principales: Tzartos, John S, Zisimopoulou, Paraskevi, Rentzos, Michael, Karandreas, Nikos, Zouvelou, Vasiliki, Evangelakou, Panagiota, Tsonis, Anastasios, Thomaidis, Thomas, Lauria, Giuseppe, Andreetta, Francesca, Mantegazza, Renato, Tzartos, Socrates J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212481/
https://www.ncbi.nlm.nih.gov/pubmed/25356387
http://dx.doi.org/10.1002/acn3.26