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Association of TCF7L2 variation with single islet autoantibody expression in children with type 1 diabetes

BACKGROUND: The transcription factor 7-like 2 (TCF7L2) gene has the strongest genetic association with type 2 diabetes. TCF7L2 also associates with latent autoimmune diabetes in adults, which often presents with a single islet autoantibody, but not with classical type 1 diabetes. METHODS: We aimed t...

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Detalles Bibliográficos
Autores principales: Redondo, Maria J, Muniz, Jesse, Rodriguez, Luisa M, Iyer, Dinakar, Vaziri-Sani, Fariba, Haymond, Morey W, Hampe, Christiane S, Metzker, Michael L, Grant, Struan F A, Balasubramanyam, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212574/
https://www.ncbi.nlm.nih.gov/pubmed/25452857
http://dx.doi.org/10.1136/bmjdrc-2013-000008