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A transgenic mouse line for collecting ribosome-bound mRNA using the tetracycline transactivator system

Acquiring the gene expression profiles of specific neuronal cell-types is important for understanding their molecular identities. Genome-wide gene expression profiles of genetically defined cell-types can be acquired by collecting and sequencing mRNA that is bound to epitope-tagged ribosomes (TRAP;...

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Detalles Bibliográficos
Autores principales: Drane, Laurel, Ainsley, Joshua A., Mayford, Mark R., Reijmers, Leon G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212621/
https://www.ncbi.nlm.nih.gov/pubmed/25400545
http://dx.doi.org/10.3389/fnmol.2014.00082