Time Course of the Changes in Novel Trioxane Antimalarial 99/411 Pharmacokinetics upon Antiepileptic Drugs Co-Administration in SD Rats

Objective. The study aimed to evaluate the influences of coadministration of antiepileptic drugs (AEDs) on an antimalarial candidate 99/411 pharmacokinetic (PK) profile. Method. For this, single oral dose PK drug interaction studies were conducted between 99/411 and FDA approved AEDs, namely, Phenyt...

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Detalles Bibliográficos
Autores principales: Singh, Yeshwant, Kushwaha, Hari Narayan, Misra, Anamika, Hidau, Mahendra Kumar, Singh, Shio Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212661/
https://www.ncbi.nlm.nih.gov/pubmed/25383231
http://dx.doi.org/10.1155/2014/756965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212661/
https://www.ncbi.nlm.nih.gov/pubmed/25383231
http://dx.doi.org/10.1155/2014/756965

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