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Time Course of the Changes in Novel Trioxane Antimalarial 99/411 Pharmacokinetics upon Antiepileptic Drugs Co-Administration in SD Rats

Objective. The study aimed to evaluate the influences of coadministration of antiepileptic drugs (AEDs) on an antimalarial candidate 99/411 pharmacokinetic (PK) profile. Method. For this, single oral dose PK drug interaction studies were conducted between 99/411 and FDA approved AEDs, namely, Phenyt...

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Detalles Bibliográficos
Autores principales:	Singh, Yeshwant, Kushwaha, Hari Narayan, Misra, Anamika, Hidau, Mahendra Kumar, Singh, Shio Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212661/ https://www.ncbi.nlm.nih.gov/pubmed/25383231 http://dx.doi.org/10.1155/2014/756965

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