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Bromelain Surface Modification Increases the Diffusion of Silica Nanoparticles in the Tumor Extracellular Matrix

[Image: see text] Tumor extracellular matrix (ECM) represents a major obstacle to the diffusion of therapeutics and drug delivery systems in cancer parenchyma. This biological barrier limits the efficacy of promising therapeutic approaches including the delivery of siRNA or agents intended for therm...

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Detalles Bibliográficos
Autores principales: Parodi, Alessandro, Haddix, Seth G., Taghipour, Nima, Scaria, Shilpa, Taraballi, Francesca, Cevenini, Armando, Yazdi, Iman K., Corbo, Claudia, Palomba, Roberto, Khaled, Sm Z., Martinez, Jonathan O., Brown, Brandon S., Isenhart, Lucas, Tasciotti, Ennio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212787/
https://www.ncbi.nlm.nih.gov/pubmed/25119793
http://dx.doi.org/10.1021/nn502807n