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BioGPS Descriptors for Rational Engineering of Enzyme Promiscuity and Structure Based Bioinformatic Analysis

A new bioinformatic methodology was developed founded on the Unsupervised Pattern Cognition Analysis of GRID-based BioGPS descriptors (Global Positioning System in Biological Space). The procedure relies entirely on three-dimensional structure analysis of enzymes and does not stem from sequence or s...

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Detalles Bibliográficos
Autores principales: Ferrario, Valerio, Siragusa, Lydia, Ebert, Cynthia, Baroni, Massimo, Foscato, Marco, Cruciani, Gabriele, Gardossi, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212942/
https://www.ncbi.nlm.nih.gov/pubmed/25353170
http://dx.doi.org/10.1371/journal.pone.0109354