Oxidative Stress Induces Persistent Telomeric DNA Damage Responsible for Nuclear Morphology Change in Mammalian Cells

One main function of telomeres is to maintain chromosome and genome stability. The rate of telomere shortening can be accelerated significantly by chemical and physical environmental agents. Reactive oxygen species are a source of oxidative stress and can produce modified bases (mainly 8-oxoG) and s...

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Detalles Bibliográficos
Autores principales: Coluzzi, Elisa, Colamartino, Monica, Cozzi, Renata, Leone, Stefano, Meneghini, Carlo, O’Callaghan, Nathan, Sgura, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212976/
https://www.ncbi.nlm.nih.gov/pubmed/25354277
http://dx.doi.org/10.1371/journal.pone.0110963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212976/
https://www.ncbi.nlm.nih.gov/pubmed/25354277
http://dx.doi.org/10.1371/journal.pone.0110963

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