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Designing a Multimer Allergen for Diagnosis and Immunotherapy of Dog Allergic Patients

BACKGROUND: Dog dander extract used for diagnosis and allergen-specific immunotherapy is often of variable and of poor quality. OBJECTIVE: To assemble four well-established dog allergen components into one recombinant folded protein for improved diagnosis and vaccination of allergy to dog. METHODS:...

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Detalles Bibliográficos
Autores principales: Nilsson, Ola B., Neimert-Andersson, Theresa, Bronge, Mattias, Grundström, Jeanette, Sarma, Ranjana, Uchtenhagen, Hannes, Kikhney, Alexey, Sandalova, Tatyana, Holmgren, Erik, Svergun, Dmitri, Achour, Adnane, van Hage, Marianne, Grönlund, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212987/
https://www.ncbi.nlm.nih.gov/pubmed/25353166
http://dx.doi.org/10.1371/journal.pone.0111041