MiR-101 Induces Senescence and Prevents Apoptosis in the Background of DNA Damage in MCF7 Cells

Moderately increased DNA damage due to the exogenous miR-101 (4 fold) over-expression in MCF7 cells was substantiated by an increase in the number of γ-H2AX foci, correlating with a simple-to-do Halo-assay. miR-101 induced mild/moderate DNA damage favoured senescence rather than apoptosis. An experi...

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Detalles Bibliográficos
Autores principales: Manvati, Siddharth, Mangalhara, Kailash Chandra, Kalaiarasan, P., Srivastava, Niloo, Kumar, Bhupender, Bamezai, R. N. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213038/
https://www.ncbi.nlm.nih.gov/pubmed/25353636
http://dx.doi.org/10.1371/journal.pone.0111177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213038/
https://www.ncbi.nlm.nih.gov/pubmed/25353636
http://dx.doi.org/10.1371/journal.pone.0111177

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