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Cortical neurogenesis in the absence of centrioles

Neuronal production in the mammalian cortex depends on extensive mitoses of radial glial progenitors (RGPs) residing in the ventricular zone (VZ). Here, we examine the function of centrioles in RGPs during cortical neurogenesis in mice by conditional removal of SAS-4, a protein required for centriol...

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Detalles Bibliográficos
Autores principales: Insolera, Ryan, Bazzi, Hisham, Shao, Wei, Anderson, Kathryn V., Shi, Song-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213237/
https://www.ncbi.nlm.nih.gov/pubmed/25282615
http://dx.doi.org/10.1038/nn.3831