Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome

BACKGROUND: Common genetic variation and rare mutations in genes encoding calcium channel subunits have pleiotropic effects on risk for multiple neuropsychiatric disorders, including autism spectrum disorder (ASD) and schizophrenia. To gain further mechanistic insights by extending previous gene exp...

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Detalles Bibliográficos
Autores principales: Tian, Yuan, Voineagu, Irina, Paşca, Sergiu P, Won, Hyejung, Chandran, Vijayendran, Horvath, Steve, Dolmetsch, Ricardo E, Geschwind, Daniel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213483/
https://www.ncbi.nlm.nih.gov/pubmed/25360157
http://dx.doi.org/10.1186/s13073-014-0075-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213483/
https://www.ncbi.nlm.nih.gov/pubmed/25360157
http://dx.doi.org/10.1186/s13073-014-0075-5

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