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Prion Protein-Specific Antibodies-Development, Modes of Action and Therapeutics Application

Prion diseases or Transmissible Spongiform Encephalopathies (TSEs) are lethal neurodegenerative disorders involving the misfolding of the host encoded cellular prion protein, PrP(C). This physiological form of the protein is expressed throughout the body, and it reaches the highest levels in the cen...

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Detalles Bibliográficos
Autores principales: Rovis, Tihana Lenac, Legname, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213558/
https://www.ncbi.nlm.nih.gov/pubmed/25275428
http://dx.doi.org/10.3390/v6103719