Mutation of the Highly Conserved Ser-40 of the HIV-1 p6 Gag Protein to Phe Causes the Formation of a Hydrophobic Patch, Enhances Membrane Association, and Polyubiquitination of Gag

The HIV-1 p6 Gag protein contains two late assembly (l-) domains that recruit proteins of the endosomal sorting complex required for transport (ESCRT) pathway to mediate membrane fission between the nascent virion and the cell membrane. It was recently demonstrated that mutation of the highly conser...

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Detalles Bibliográficos
Autores principales: Hahn, Friedrich, Setz, Christian, Friedrich, Melanie, Rauch, Pia, Solbak, Sara Marie, Frøystein, Nils Åge, Henklein, Petra, Votteler, Jörg, Fossen, Torgils, Schubert, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213559/
https://www.ncbi.nlm.nih.gov/pubmed/25279819
http://dx.doi.org/10.3390/v6103738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213559/
https://www.ncbi.nlm.nih.gov/pubmed/25279819
http://dx.doi.org/10.3390/v6103738

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