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A Loop Region in the N-Terminal Domain of Ebola Virus VP40 Is Important in Viral Assembly, Budding, and Egress

Ebola virus (EBOV) causes viral hemorrhagic fever in humans and can have clinical fatality rates of ~60%. The EBOV genome consists of negative sense RNA that encodes seven proteins including viral protein 40 (VP40). VP40 is the major Ebola virus matrix protein and regulates assembly and egress of in...

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Detalles Bibliográficos
Autores principales: Adu-Gyamfi, Emmanuel, Soni, Smita P., Jee, Clara S., Digman, Michelle A., Gratton, Enrico, Stahelin, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213565/
https://www.ncbi.nlm.nih.gov/pubmed/25330123
http://dx.doi.org/10.3390/v6103837