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Challenges in the Design of a T Cell Vaccine in the Context of HIV-1 Diversity
The extraordinary variability of HIV-1 poses a major obstacle to vaccine development. The effectiveness of a vaccine is likely to vary dramatically in different populations infected with different HIV-1 subtypes, unless innovative vaccine immunogens are developed to protect against the range of HIV-...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213573/ https://www.ncbi.nlm.nih.gov/pubmed/25341662 http://dx.doi.org/10.3390/v6103968 |