Real-time observation of signal recognition particle binding to actively translating ribosomes

The signal recognition particle (SRP) directs translating ribosome-nascent chain complexes (RNCs) that display a signal sequence to protein translocation channels in target membranes. All previous work on the initial step of the targeting reaction, when SRP binds to RNCs, used stalled and non-transl...

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Detalles Bibliográficos
Autores principales: Noriega, Thomas R, Chen, Jin, Walter, Peter, Puglisi, Joseph D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213662/
https://www.ncbi.nlm.nih.gov/pubmed/25358118
http://dx.doi.org/10.7554/eLife.04418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213662/
https://www.ncbi.nlm.nih.gov/pubmed/25358118
http://dx.doi.org/10.7554/eLife.04418

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