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A zebrafish model of manganism reveals reversible and treatable symptoms that are independent of neurotoxicity

Manganese (manganese ion; referred to as Mn) is essential for neuronal function, yet it is toxic at high concentrations. Environmental and occupational exposure to high concentrations of Mn causes manganism, a well-defined movement disorder in humans, with symptoms resembling Parkinson’s disease (PD...

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Detalles Bibliográficos
Autores principales: Bakthavatsalam, Subha, Das Sharma, Shreya, Sonawane, Mahendra, Thirumalai, Vatsala, Datta, Ankona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213728/
https://www.ncbi.nlm.nih.gov/pubmed/25261567
http://dx.doi.org/10.1242/dmm.016683