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A zebrafish model of manganism reveals reversible and treatable symptoms that are independent of neurotoxicity
Manganese (manganese ion; referred to as Mn) is essential for neuronal function, yet it is toxic at high concentrations. Environmental and occupational exposure to high concentrations of Mn causes manganism, a well-defined movement disorder in humans, with symptoms resembling Parkinson’s disease (PD...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213728/ https://www.ncbi.nlm.nih.gov/pubmed/25261567 http://dx.doi.org/10.1242/dmm.016683 |