Loss of α-catenin elicits a cholestatic response and impairs liver regeneration

The liver is unique in its capacity to regenerate after injury, during which hepatocytes actively divide and establish cell-cell contacts through cell adhesion complexes. Here, we demonstrate that the loss of α-catenin, a well-established adhesion component, dramatically disrupts liver regeneration....

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Detalles Bibliográficos
Autores principales: Herr, Keira Joann, Tsang, Ying-hung Nicole, Ong, Joanne Wei En, Li, Qiushi, Yap, Lai Lai, Yu, Weimiao, Yin, Hao, Bogorad, Roman L., Dahlman, James E., Chan, Yee Gek, Bay, Boon Huat, Singaraja, Roshni, Anderson, Daniel G., Koteliansky, Victor, Viasnoff, Virgile, Thiery, Jean Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213774/
https://www.ncbi.nlm.nih.gov/pubmed/25355493
http://dx.doi.org/10.1038/srep06835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213774/
https://www.ncbi.nlm.nih.gov/pubmed/25355493
http://dx.doi.org/10.1038/srep06835

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