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Ginseng total saponin modulates the changes of α-actinin-4 in podocytes induced by diabetic conditions

BACKGROUND: The actin cytoskeleton in podocytes is essential for the maintenance of its normal structure and function. Its disruption is a feature of podocyte foot-process effacement and is associated with proteinuria. α-Actinin-4 in podocytes serves as a linker protein binding the actin filaments o...

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Detalles Bibliográficos
Autores principales: Ha, Tae-Sun, Choi, Ji-Young, Park, Hye-Young, Nam, Ja-Ae, Seong, Su-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213837/
https://www.ncbi.nlm.nih.gov/pubmed/25379001
http://dx.doi.org/10.1016/j.jgr.2014.05.004