HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform

Muscle specific receptor tyrosine kinase (MuSK) is an essential postsynaptic transmembrane molecule that mediates clustering of acetylcholine receptors (AChR). MUSK exon 10 is alternatively skipped in human, but not in mouse. Skipping of this exon disrupts a cysteine-rich region (Fz-CRD), which is e...

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Detalles Bibliográficos
Autores principales: Nasrin, Farhana, Rahman, Mohammad Alinoor, Masuda, Akio, Ohe, Kenji, Takeda, Jun-ichi, Ohno, Kinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213890/
https://www.ncbi.nlm.nih.gov/pubmed/25354590
http://dx.doi.org/10.1038/srep06841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213890/
https://www.ncbi.nlm.nih.gov/pubmed/25354590
http://dx.doi.org/10.1038/srep06841

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