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Impairment of Hepatic and Renal Functions by 2,5-Hexanedione Is Accompanied by Oxidative Stress in Rats

2,5-Hexanedione (2,5-HD) is the toxic metabolite of n-hexane which is widely used as solvent in numerous industries. The present study elucidated the precise mechanism of 2,5-HD in hepatorenal toxicity by determining the involvement of oxidative stress in rats. Adult male Wistar rats were exposed to...

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Detalles Bibliográficos
Autores principales: Adedara, Isaac A., Abolaji, Amos O., Odion, Blessing E., Okwudi, Isioma J., Omoloja, Abiola A., Farombi, Ebenezer O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214033/
https://www.ncbi.nlm.nih.gov/pubmed/25379039
http://dx.doi.org/10.1155/2014/239240