DNA methylation and demethylation as targets for antipsychotic therapy

Schizophrenia (SZ) and bipolar disorder (BPD) patients show a downregulation of GAD67, reelin (RELN), brain-derived neurotrophic factor (BDNF), and other genes expressed in telencephalic GABAergic and glutamatergic neurons. This downregulation is associated with the enrichment of 5-methylcytosine an...

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Detalles Bibliográficos
Autores principales: Guidotti, Alessandro, Grayson, Dennis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Les Laboratoires Servier 2014
Materias:
Pharmacological Aspects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214182/
https://www.ncbi.nlm.nih.gov/pubmed/25364290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214182/
https://www.ncbi.nlm.nih.gov/pubmed/25364290

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