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Inhibition of Src phosphorylation reduces damage to the blood-brain barrier following transient focal cerebral ischemia in rats

The disruption of the blood-brain barrier (BBB) caused by cerebral ischemia determines the extent of injury and patient prognosis. Inhibitors of Src can markedly minimize the infarct size and preserve neurological function. The Src protein tyrosine kinase (PTK) inhibitor, PP2, protects the rat brain...

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Detalles Bibliográficos
Autores principales: BAI, YONGSHENG, XU, GUANGHUI, XU, MENGXUE, LI, QI, QIN, XINYUE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214349/
https://www.ncbi.nlm.nih.gov/pubmed/25269821
http://dx.doi.org/10.3892/ijmm.2014.1946