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Secreted frizzled-related protein 2 is epigenetically silenced and functions as a tumor suppressor in oral squamous cell carcinoma

The role of epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) and its functions in the development of oral squamous cell carcinoma (OSCC) remain to be elucidated. The present study demonstrated that SFRP2 mRNA was detected in 97.96% of tumor-adjacent normal tissues, while its ex...

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Detalles Bibliográficos
Autores principales: XIAO, CAN, WANG, LILI, ZHU, LIFANG, ZHANG, CHENPING, ZHOU, JIANHUA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214353/
https://www.ncbi.nlm.nih.gov/pubmed/25189527
http://dx.doi.org/10.3892/mmr.2014.2542