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Double stranded RNA-dependent protein kinase promotes the tumorigenic phenotype in HepG2 hepatocellular carcinoma cells by activating STAT3

Previously known as a first-response protein upon viral infection and other stress signals, double-stranded RNA-dependent protein kinase (PKR, also termed EIF2AK2) has been found to be differentially expressed in multiple types of tumor, including hepatocellular carcinoma, suggesting that PKR may be...

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Detalles Bibliográficos
Autores principales: WANG, XUN, DONG, JIA-HONG, ZHANG, WEN-ZHI, LENG, JIAN-JUN, CAI, SHOU-WANG, CHEN, MING-YI, YANG, XUERUI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214393/
https://www.ncbi.nlm.nih.gov/pubmed/25360179
http://dx.doi.org/10.3892/ol.2014.2560