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Antiproliferative and apoptotic effects of telmisartan in human colon cancer cells

Telmisartan is an angiotensin I (AT(1)) receptor blocker used in the treatment of essential hypertension, with partial peroxisome proliferator-activated receptor γ (PPARγ) agonism. In prior studies, PPARγ activation led to apoptosis and cell cycle inhibition in various cancer cells. The aim of the p...

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Detalles Bibliográficos
Autores principales: LEE, LUCAS D., MAFURA, BENJAMIN, LAUSCHER, JOHANNES C., SEELIGER, HENDRIK, KREIS, MARTIN E., GRÖNE, JÖRN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214397/
https://www.ncbi.nlm.nih.gov/pubmed/25360175
http://dx.doi.org/10.3892/ol.2014.2592