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Establishment of an orthotopic transplantation tumor model in nude mice using a drug-resistant human ovarian cancer cell line with a high expression of c-Kit

The resistance of ovarian cancer to platinum-based chemotherapy is a critical issue in the clinical setting. The present study aimed to establish animal models to replicate this clinical condition, as well as to investigate the resistance mechanisms of ovarian cancer. A cisplatin (DDP)-resistant hum...

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Detalles Bibliográficos
Autores principales: YI, CUNJIAN, ZHANG, LEI, LI, LI, LIU, XIANGQIONG, LING, SHENGRONG, ZHANG, FAYUN, LIANG, WEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214472/
https://www.ncbi.nlm.nih.gov/pubmed/25364436
http://dx.doi.org/10.3892/ol.2014.2537