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Immunostaining and time-lapse analysis of vinblastine-induced paracrystal formation in human A549 cells

Vinblastine is a vinca alkaloid that binds to tubulin and inhibits microtubule formation in cells. Vinblastine treatment results in the formation of paracrystalline aggregates in the cells, which are formed from tightly packed tubulin molecules. Mitotic spindle assemblies in treated cells are disrup...

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Detalles Bibliográficos
Autores principales: NAKAMURA, YUKA, ISHIGAKI, YASUHITO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214480/
https://www.ncbi.nlm.nih.gov/pubmed/25364400
http://dx.doi.org/10.3892/ol.2014.2549