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Immunostaining and time-lapse analysis of vinblastine-induced paracrystal formation in human A549 cells
Vinblastine is a vinca alkaloid that binds to tubulin and inhibits microtubule formation in cells. Vinblastine treatment results in the formation of paracrystalline aggregates in the cells, which are formed from tightly packed tubulin molecules. Mitotic spindle assemblies in treated cells are disrup...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214480/ https://www.ncbi.nlm.nih.gov/pubmed/25364400 http://dx.doi.org/10.3892/ol.2014.2549 |