The Route of HIV Escape from Immune Response Targeting Multiple Sites Is Determined by the Cost-Benefit Tradeoff of Escape Mutations

Cytotoxic T lymphocytes (CTL) are a major factor in the control of HIV replication. CTL arise in acute infection, causing escape mutations to spread rapidly through the population of infected cells. As a result, the virus develops partial resistance to the immune response. The factors controlling th...

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Detalles Bibliográficos
Autores principales: Batorsky, Rebecca, Sergeev, Rinat A., Rouzine, Igor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214571/
https://www.ncbi.nlm.nih.gov/pubmed/25356981
http://dx.doi.org/10.1371/journal.pcbi.1003878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214571/
https://www.ncbi.nlm.nih.gov/pubmed/25356981
http://dx.doi.org/10.1371/journal.pcbi.1003878

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