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Telomeric ORFs (TLOs) in Candida spp. Encode Mediator Subunits That Regulate Distinct Virulence Traits

The TLO genes are a family of telomere-associated ORFs in the fungal pathogens Candida albicans and C. dubliniensis that encode a subunit of the Mediator complex with homology to Med2. The more virulent pathogen C. albicans has 15 copies of the gene whereas the less pathogenic species C. dubliniensi...

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Detalles Bibliográficos
Autores principales: Haran, John, Boyle, Hannah, Hokamp, Karsten, Yeomans, Tim, Liu, Zhongle, Church, Michael, Fleming, Alastair B., Anderson, Matthew Z., Berman, Judith, Myers, Lawrence C., Sullivan, Derek J., Moran, Gary P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214616/
https://www.ncbi.nlm.nih.gov/pubmed/25356803
http://dx.doi.org/10.1371/journal.pgen.1004658